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A B C E File G H K L M N O P R S T U V     ×The narcotic antagonists, naloxone or nalmefene, are precise antidotes for opioid overdose. Opioid antagonists shouldn't be administered in the absence of clinically major respiratory or circulatory despair secondary to ROXICODONE® overdose. If needed the right dose of naloxone hydrochloride or nalmef